Beyond blood safety

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Discarded infected blood units prove screening works, but also expose urgent gaps in disease prevention — surveillance, testing, and infection control — that public health can’t afford to ignore

A report published in this paper revealed that 47,375 blood units collected in Sindh during 2025 had to be discarded after screening detected transfusion-transmissible infections (TTIs), including hepatitis B, hepatitis C, HIV, syphilis and malaria. The figures showed that 5.7 per cent of screened donations — roughly one in every 20 units — were found unsafe for transfusion.

There is reassurance in the fact that screening systems are identifying infected blood before it reaches patients. Yet the findings also expose a deeper public-health challenge. Every discarded unit represents an individual carrying an infection, often without knowing it. Blood banks, therefore, are not merely repositories of blood; they also provide a valuable glimpse into the prevalence of infectious diseases in the wider community.

The persistence of these infection rates should be a matter of concern. Hepatitis C remains the most frequently detected infection among donors, followed by hepatitis B and syphilis, while HIV-positive donations, though fewer, continue to appear in screening records. These are not simply blood-bank statistics; they are indicators of ongoing transmission and undiagnosed disease.

                                                                                  Courtesy: PMA
The report also highlighted Sindh's continuing dependence on replacement donors. Only about 15 per cent of donations came from voluntary donors, while the overwhelming majority were arranged through family members or replacement donors. This model has long been regarded as less desirable than one built on regular voluntary, non-remunerated donations. Individuals donating under social or family pressure may be less willing to disclose potential health risks, while repeat voluntary donors generally constitute a safer and more reliable donor pool. Expanding voluntary blood donation is, therefore, not merely a matter of increasing supplies; it is also a crucial component of improving blood safety.

More importantly, the figures compel a broader assessment of disease-control efforts. The continued prevalence of hepatitis B, hepatitis C and HIV among apparently healthy blood donors suggests that large numbers of infections remain undiagnosed in the community. This raises legitimate questions about the reach and effectiveness of public awareness campaigns, screening initiatives, vaccination programmes and infection-control measures. Blood banks are detecting infections at the final checkpoint before transfusion; ideally, public-health systems should identify and prevent many of these infections much earlier.

Blood safety cannot be separated from wider public-health realities. Unsafe injections, poor infection-control practices, unregulated procedures and delayed diagnosis all contribute to the pool of infections that eventually appear in blood donor statistics. While blood banks prevent infected blood from reaching patients, they cannot by themselves address the causes that produce these infections.

The thousands of infected blood units discarded each year are evidence that screening safeguards are functioning. Yet they also point to a more uncomfortable reality: the burden of preventable infectious diseases remains far too high. The challenge before policymakers is not simply to keep unsafe blood out of hospitals, but to reduce the number of infected individuals entering the donor pool in the first place. This requires health authorities to critically review the effectiveness of existing disease-control programmes, strengthen surveillance and testing, improve infection-control practices and expand access to treatment. A sustained commitment to voluntary blood donation must form part of that effort. Until measurable progress is achieved, blood bank statistics will continue to serve as a reminder of unfinished business in public health.

(Originally published in the weekly Social Track, Karachi)

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